生命科学资讯

The master virulence regulator PhoP dictates carbon metabolism by controlling cyclic AMP synthesis in Salmonella

Paralogs of Slitrk cell adhesion molecules configure excitatory synapse specificity via distinct cellular mechanisms

2025: A year of resilience and resourcefulness

Most researchers would receive more recognition if assessed by article-level metrics than by journal-level metrics

Biased sampling driven by bacterial population structure confounds machine learning prediction of antimicrobial resistance

The Drosophila escape motor circuit shows differential vulnerability to aging linked to functional decay

USPPAR is a cost-effective, scalable, and highly sensitive single-cell RNA sequencing workflow compatible with diverse specimens

Bacterial gene 5′ ends have unusual mutation rates that can mislead tests of selection

When two signals are better than one: Synergistic control of erythropoiesis

Identification of sporulation genes in Bacillus anthracis highlights similarities and significant differences with Bacillus subtilis

Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation

A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and capacity for intra-species co-operation

Activation of the ciliary kinase CDKL5 is mediated by the cyclin-dependent kinase CDK20/LF2 to control flagellar length

IL-17 stimulates erythropoiesis in vivo by amplifying the response of erythroid progenitors to erythropoietin

A colorful legacy of hybridization in wood-warblers includes frequent sharing of carotenoid genes among species and genera

Plasmid streamlining drives the extinction of antibiotic resistance plasmids under selection for horizontal transmission

Adaptations of the axon initial segment in fast-spiking interneurons of the human neocortex support low action potential thresholds

Male bonobo mating strategies target female fertile windows despite noisy ovulatory signals during sexual swelling

The luminal ring protein C2CD3 acts as a radial in-to-out organizer of the distal centriole and appendages

Structures of G-protein coupled receptor HCAR3 in complex with selective agonists reveal the basis for ligand recognition and selectivity