生命科学资讯

A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito

Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism

De novo design of a peptide modulator to reverse sodium channel dysfunction linked to cardiac arrhythmias and epilepsy

Multiscale proteomic modeling reveals protein networks driving Alzheimer’s disease pathogenesis

Human monoclonal antibodies targeting A35 protect from death caused by mpox

IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity

Transient gene melting governs the timing of oligodendrocyte maturation

Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection

Structurally conserved human anti-A35 antibodies protect mice and macaques from mpox virus infection

Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons

RNA Pol II inhibition activates cell death independently from the loss of transcription

Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy

Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

A unified cell atlas of vascular plants reveals cell-type foundational genes and accelerates gene discovery

Charting the landscape of cytoskeletal diversity in microbial eukaryotes

Coalescing single-cell genomes and transcriptomes to decode breast cancer progression

Zebrafish use spectral information to suppress the visual background

Generation of antigen-specific paired-chain antibodies using large language models

Gut-to-brain signaling restricts dietary protein intake during recovery from catabolic states

Disparate leukemia mutations converge on nuclear phase-separated condensates