生命科学资讯

UCB boards T cell engager train in $60M upfront deal with Antengene

SLC4A1 mutations that cause distal renal tubular acidosis alter cytoplasmic pH and cellular autophagy

Pierre Fabre seeks to revive US approval chances for spurned cell therapy

Intracellular expression of a fluorogenic DNA aptamer using retron Eco2

Why it’s critical to close open steps in cell therapy manufacturing

Citrate clearance is a major function of aconitase 2 in the canonical TCA cycle

Pyruvate is a natural suppressor of interferon signaling by inducing STAT1 protein pyruvylation

High-resolution in situ structures of hantavirus glycoprotein tetramers

As CAR-T cell therapy gains ground on solid tumors, regulatory red tape hinders progress

Genetic network shaping Kenyon cell identity and function in Drosophila mushroom bodies

Single-cell ultra-high-throughput multiplexed chromatin accessibility and gene expression sequencing (SUM-seq) - Nature

Organism-wide cellular dynamics and epigenomic remodeling in mammalian aging | Science

A cellular basis for the mammalian nocturnal-diurnal switch | Science

Reconstitution of sex determination and the testicular niche using mouse pluripotent stem cells | Science

A Live-Cell NanoBRET Assay Shines Light on Toxic RNA–Protein Interactions in Myotonic Dystrophy

Whole-organ and whole-body 3D atlases enable cellome-wide profiling

Nuclear speckles enable processing of RNA from GC-rich isochores

Large-scale proteomics across neurological disorders uncovers biomarker panel and targets in multiple sclerosis

The MicrobeAtlas database: Global trends and insights into Earth’s microbial ecosystems

Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease