生命科学资讯

Citrate clearance is a major function of aconitase 2 in the canonical TCA cycle

Pyruvate is a natural suppressor of interferon signaling by inducing STAT1 protein pyruvylation

High-resolution in situ structures of hantavirus glycoprotein tetramers

As CAR-T cell therapy gains ground on solid tumors, regulatory red tape hinders progress

Genetic network shaping Kenyon cell identity and function in Drosophila mushroom bodies

Single-cell ultra-high-throughput multiplexed chromatin accessibility and gene expression sequencing (SUM-seq) - Nature

Organism-wide cellular dynamics and epigenomic remodeling in mammalian aging | Science

A cellular basis for the mammalian nocturnal-diurnal switch | Science

Reconstitution of sex determination and the testicular niche using mouse pluripotent stem cells | Science

A Live-Cell NanoBRET Assay Shines Light on Toxic RNA–Protein Interactions in Myotonic Dystrophy

Whole-organ and whole-body 3D atlases enable cellome-wide profiling

Nuclear speckles enable processing of RNA from GC-rich isochores

Large-scale proteomics across neurological disorders uncovers biomarker panel and targets in multiple sclerosis

The MicrobeAtlas database: Global trends and insights into Earth’s microbial ecosystems

Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease

LUMI-lab: A foundation model-driven autonomous platform enabling discovery of ionizable lipid designs for mRNA delivery

Editing strigolactone hormone receptor for robust antiviral silencing in rice

A regulatory network promotes apoplastic alkalinization to prime plant immunity in tissues distal to site of infection

Fungal-derived cellobiose metabolic pathway fuels T cells to bypass intratumoral glucose competition

Vir climbs on Astellas deal, study results for ‘masked’ T cell engager