生命科学资讯

Giant DNA viruses encode a hallmark translation initiation complex of eukaryotic life

Cell cycle-dependent cues regulate temporal patterning of the Drosophila central brain neural stem cells

Cell therapy company hopes to end Tokyo biotech IPO drought with $92M offering

Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux

A single-cell time-series atlas of endothelial cell embryonic development

Selecting the optimal cell therapy manufacturing platform

Deep neural networks to register and annotate cells in moving and deforming nervous systems

SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo

CLIM-TIME identifies metastatic microenvironment modulators for T cell therapy response

Persistent T cell activation and cytotoxicity against glioblastoma following single oncolytic virus treatment in a clinical trial

Tumor, immune and neural cells are involved in cancer cachexia

Cdc42 interacts with chaperone Ydj1 to enhance its stability and partitioning during asymmetric cell division and aging in yeast

Lilly’s $2.4B bet on off-the-shelf cell therapy is part of a wider Big Pharma shift

Single-cell atlas of AML reveals age-related gene regulatory networks in t(8;21) AML

Planetary microbiome structure and generalist-driven gene flow across disparate habitats

CUL5 E3 ubiquitin ligase regulates the evasion of bladder cancer cells to CD8+ T cell-mediated killing by inhibiting autophagy

Navigating the complexities of Cell and Gene Therapy supply chains

Mouse skeletal muscle satellite cells co-opt the tenogenic gene Scleraxis to instruct regeneration