生命科学资讯
生物技术与制药领域的最新动态
SETDB1通过在小鼠胚胎中消除MERVL驱动的二细胞全能性转录程序,实现胚胎发育超越卵裂阶段。
SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo
单分子计数检测海马和纹状体突触中的低拷贝甘氨酸受体
Single molecule counting detects low-copy glycine receptors in hippocampal and striatal synapses
作为精细触觉感知中摩擦系数的替代方案:摩擦不稳定性
Frictional instabilities as an alternative to friction coefficient in fine touch perception
基于人群水平循环阈值预测SARS-CoV-2传播动态:一项流行病传播与机器学习建模研究
Prediction of SARS-CoV-2 transmission dynamics based on population-level cycle threshold values: An epidemic transmission and machine learning modeling study
通过模块化递归神经网络进行误差信号的伴随传播以实现生物学上合理的学习
Adjoint propagation of error signal through modular recurrent neural networks for biologically plausible learning
工作记忆中时间的突触足迹
Synaptic footprints of time in working memory
RNA聚合酶I介导的核糖体RNA合成易发生转录提前终止
Ribosomal RNA synthesis by RNA polymerase I is subject to premature termination of transcription
BICC1与PKD1和PKD2相互作用,驱动ADPKD中的囊肿形成
BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKD
更正:精氨酸通过调控TSC2-Rheb信号轴调节mTORC1活性
Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
单细胞图谱揭示t(8;21)急性髓系白血病中与年龄相关的基因调控网络
Single-cell atlas of AML reveals age-related gene regulatory networks in t(8;21) AML
四位女性先驱者的科学贡献长期被忽视
Four women whose pioneering contributions to science have been largely overlooked
35项性状多基因指数与死亡率的异质性关联:一项基于登记链接人群的随访研究
Heterogeneous associations of polygenic indices of 35 traits with mortality: a register-linked population-based follow-up study
后向条件反射揭示边缘下皮层抑制性记忆的灵活性
Backward conditioning reveals flexibility in infralimbic cortex inhibitory memories
大鼠前额叶皮层2/3层反复兴奋性突触的短期促进源于可释放池的渐进性过度填充
Progressive overfilling of readily releasable pool underlies short-term facilitation at recurrent excitatory synapses in layer 2/3 of the rat prefrontal cortex
基于压缩感知的方法识别驱动习得性病原体回避的模块化神经回路
Compressed sensing-based approach identifies modular neural circuitry driving learned pathogen avoidance
掌控感能缓冲压力
Sense of control buffers against stress
<i>map3k1</i>基因是涡虫中祖细胞分化空间限制的必要条件
map3k1 is required for spatial restriction of progenitor differentiation in planarians
性肽靶向大脑中不同的高级处理神经元,以诱导雌性交配后反应。
Sex peptide targets distinct higher order processing neurons in the brain to induce the female post-mating response
非结构化α-微管蛋白C末端尾部的可及性受微管晶格构象调控
Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation