生命科学资讯
生物技术与制药领域的最新动态
<i>SLC4A1</i>基因突变致远端肾小管酸中毒,改变细胞质pH并影响细胞自噬
SLC4A1 mutations that cause distal renal tubular acidosis alter cytoplasmic pH and cellular autophagy
更正:在斑马鱼端粒缩短时,p53与mTOR/AKT的对抗促进体内从凋亡向衰老的转变
Correction: Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish
H3K115乙酰化与CpG岛启动子和活性调控位点的脆弱核小体相关
Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites
古老光感受器塑造行为反应
Ancient photoreceptor shapes behavioural responses
利用逆转录子Eco2在细胞内表达荧光DNA适配体
Intracellular expression of a fluorogenic DNA aptamer using retron Eco2
通过体内注射和电穿孔裸mRNA恢复少弱畸精子症小鼠的精子活力
Sperm motility in mice with oligo-astheno-teratozoospermia restored by in vivo injection and electroporation of naked mRNA
统计学习过程中期望的可分离动态效应
Dissociable dynamic effects of expectation during statistical learning
迈向猕猴社会容忍度等级的神经解剖学与认知基础研究
Toward neuroanatomical and cognitive foundations of macaque social tolerance grades
基于纳米孔直接RNA测序数据的RNA修饰估计原始信号分割
Raw signal segmentation for estimating RNA modification from Nanopore direct RNA sequencing data
JAX动物行为系统(JABS):一款基于遗传学信息、端到端的高级实验室小鼠行为表型分析平台。
JAX Animal Behavior System (JABS), a genetics-informed, end-to-end advanced behavioral phenotyping platform for the laboratory mouse
基于代理模型揭示蝙蝠如何在密集群体出没中导航
Agent-based modeling reveals how bats navigate dense group emergences
利用亚突触靶向GCaMP8变体解析突触事件
Resolving synaptic events using subsynaptically targeted GCaMP8 variants
方向感
A sense of direction
冈比亚跨牧牛系统中裂谷热病毒动态研究
Rift Valley fever virus dynamics in a transhumant cattle system in The Gambia
<i>果蝇</i>蘑菇体中塑造凯尼恩细胞身份与功能的遗传网络
Genetic network shaping Kenyon cell identity and function in Drosophila mushroom bodies
视神经损伤后ATF4协调轴突再生与神经退行性转录程序的双向调控
Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by ATF4 following optic nerve injury
大规模并行报告基因分析用于单核苷酸分辨率下基因特异性调控区域的定位
Massively parallel reporter assay for mapping gene-specific regulatory regions at single-nucleotide resolution
人类内嗅皮层中抽象结构知识的灵活神经表征
Flexible neural representations of abstract structural knowledge in the human entorhinal cortex
针对RAS驱动型癌症的合成基因电路选择性靶向
Synthetic gene circuits that selectively target RAS-driven cancers