生命科学资讯
生物技术与制药领域的最新动态
Piriform seizures mediated by the piriform-entorhino-dentate circuit induce brain-wide functional reorganization in mice
Integrated chromatin and transcriptomic profiling reveals sex-specific mechanisms of gene regulation in hepatic nutrient responses
Synapse types are spatially associated with regional hemodynamics in the mouse brain
一种用于深度突变扫描研究的经济高效且可扩展的条形码文库构建方法
A cost-effective and scalable barcoded library construction method for deep mutational scanning studies
科学改革是一场无法取胜的军备竞赛吗?
Is scientific reform an unwinnable arms race?
前顶叶伽马波段相位耦合增强促进人类利他行为
Augmentation of frontoparietal gamma-band phase coupling enhances human altruistic behavior
更正:染色体快速增减驱动真菌病原体组织胞浆菌关键形态与毒力表型
Correction: Rapid gain and loss of a chromosome drives key morphology and virulence phenotypes in the fungal pathogen Histoplasma
CUL5 E3泛素连接酶通过抑制自噬调控膀胱癌细胞逃避CD8<sup>+</sup> T细胞介导的杀伤作用
CUL5 E3 ubiquitin ligase regulates the evasion of bladder cancer cells to CD8+ T cell-mediated killing by inhibiting autophagy
微胶质细胞通过内皮核苷酸信号感知毛细血管结合的新型隐球菌荚膜成分,从而识别真菌感染。
Microglia sense fungal infections through capsular components from capillary-bound Cryptococcus neoformans via endothelial nucleotide signaling
内吞蛋白AP180组装域调控秀丽隐杆线虫突触小泡大小与释放
Endocytic protein AP180 assembly domain regulates synaptic vesicle size and release in Caenorhabditis elegans
人类背侧前扣带回促进不公平提议的接受并调节不平等厌恶
The human dorsal anterior cingulate facilitates acceptance of unfair offers and regulates inequity aversion
人类新生儿基于节奏而非旋律结构形成音乐预测
Human newborns form musical predictions based on rhythmic but not melodic structure
阴道菌群失调生态模型为研究提供新线索
An ecological model of vaginal dysbiosis provides new research leads
资源环境塑造人类阴道微生物群的组成与稳定性
Resource landscape shapes the composition and stability of the human vaginal microbiota
由RNAi或异染色质驱动的表观突变引发致病性毛霉菌的短暂抗菌药物耐药性。
Epimutations driven by RNAi or heterochromatin evoke transient antimicrobial drug resistance in pathogenic Mucor fungi
<i>Bactrocera dorsalis</i> 中 Grik2b 和 Grik2c 红藻氨酸受体调控产卵行为
Grik2b and Grik2c kainate receptors regulate oviposition in Bactrocera dorsalis
CspC:CspA异二聚体在艰难梭菌孢子萌发过程中传递萌发剂与共萌发剂信号
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination
HIV-1 Vpr诱导的DNA损伤触发表观遗传重塑与转录程序,以增强病毒转录和潜伏期再激活
DNA damage induced by HIV-1 Vpr triggers epigenetic remodeling and transcriptional programs to enhance virus transcription and latency reactivation
<i>白色念珠菌</i>应激调节因子Cap1的反复突变揭示唑类耐药性与氧化应激反应间的权衡关系
Recurrent mutations in the stress regulator Cap1 reveal a trade-off between azole resistance and oxidative stress response in Candida albicans