生命科学资讯
生物技术与制药领域的最新动态
Endocytic protein AP180 assembly domain regulates synaptic vesicle size and release in Caenorhabditis elegans
人类背侧前扣带回促进不公平提议的接受并调节不平等厌恶
The human dorsal anterior cingulate facilitates acceptance of unfair offers and regulates inequity aversion
人类新生儿基于节奏而非旋律结构形成音乐预测
Human newborns form musical predictions based on rhythmic but not melodic structure
阴道菌群失调生态模型为研究提供新线索
An ecological model of vaginal dysbiosis provides new research leads
资源环境塑造人类阴道微生物群的组成与稳定性
Resource landscape shapes the composition and stability of the human vaginal microbiota
由RNAi或异染色质驱动的表观突变引发致病性毛霉菌的短暂抗菌药物耐药性。
Epimutations driven by RNAi or heterochromatin evoke transient antimicrobial drug resistance in pathogenic Mucor fungi
<i>Bactrocera dorsalis</i> 中 Grik2b 和 Grik2c 红藻氨酸受体调控产卵行为
Grik2b and Grik2c kainate receptors regulate oviposition in Bactrocera dorsalis
CspC:CspA异二聚体在艰难梭菌孢子萌发过程中传递萌发剂与共萌发剂信号
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination
HIV-1 Vpr诱导的DNA损伤触发表观遗传重塑与转录程序,以增强病毒转录和潜伏期再激活
DNA damage induced by HIV-1 Vpr triggers epigenetic remodeling and transcriptional programs to enhance virus transcription and latency reactivation
<i>白色念珠菌</i>应激调节因子Cap1的反复突变揭示唑类耐药性与氧化应激反应间的权衡关系
Recurrent mutations in the stress regulator Cap1 reveal a trade-off between azole resistance and oxidative stress response in Candida albicans
肠道激活的NHR-86–CYP通路介导粪肠球菌益生菌在肌萎缩侧索硬化线虫模型中的神经保护作用
A gut-activated NHR-86–CYP pathway mediates the neuroprotective effects of Enterococcus faecium probiotics in a nematode model of amyotrophic lateral sclerosis
人类大脑中五种能量代谢途径呈现区域分布差异与生命周期轨迹变化
Five energy metabolism pathways show distinct regional distributions and lifespan trajectories in the human brain
更正:质粒与染色体移动遗传元件引发的基因组内冲突推动物种内自然转化的进化
Correction: Intragenomic conflicts with plasmids and chromosomal mobile genetic elements drive the evolution of natural transformation within species
人类浅层白质的微观结构特征及其与皮质几何和连接性的关联
Microstructural profiles of the human superficial white matter and their associations to cortical geometry and connectivity
修正:氧过饱和对多种水生外温动物增温耐受性影响微乎其微
Correction: Oxygen supersaturation has negligible effects on warming tolerance across diverse aquatic ectotherms
基于深度学习的计算流程预测视网膜类器官发育结果
A deep learning-based computational pipeline predicts developmental outcome in retinal organoids
脂质代谢酶HSD17B12促进PD-L1溶酶体降解,增强小鼠模型抗肿瘤免疫反应。
The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model
免疫代谢的多面性
The many facets of immunometabolism
I型和III型干扰素通过剂量依赖性激活Hippo通路抑制人支气管上皮细胞组织修复
Dose-dependent activation of the Hippo pathway by Type I and Type III interferons suppresses tissue repair by human bronchial epithelial cells