生命科学资讯

Preclinical stem cell biotech PrimeGen takes SPAC route to Nasdaq

First-in-class fusion protein reverses T-cell exhaustion across multiple models

Thermo Fisher Scientific launches kit to simplify liver cell gene expression and help advance early-stage drug discovery - SelectScience

Single-cell transcriptomics of X-ray irradiated Drosophila wing discs reveals heterogeneity related to cell-cycle status and cell location

Charles River to close cell therapy CDMO site, lay off 20 staffers

Repression of PRMT activities sensitize human homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment

10x Genomics Expands Flex Lineup with High-Throughput Single-Cell Assay Launch - MSN

Building a robust in-process testing plan for cell therapy manufacturing success

Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells

Molecular features of human pathological tau distinguish tauopathy-associated dementias

Human orbitofrontal neural activity is linked to obsessive-compulsive behavioral dynamics

Sympathetic-epithelial crosstalk governs tissue-resident memory T cell immunosurveillance in the skin

Hallmarks of cancer—Then and now, and beyond

Janux hires CMO after T cell engager deal with Bristol Myers; A batch of appointments at Lexeo

Improving atlas-scale single-cell annotation models with hierarchical cross-entropy loss - Nature

Mechanistic insights into RNA chaperoning by Ro60 and La autoantigens

A Bacteroides synthetic biology toolkit to build an in vivo malabsorption biosensor

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

A non-catalytic role for RFC in PCNA-mediated processive DNA synthesis

AstraZeneca vows $15B China investment to boost cell therapy and radioconjugate capabilities