生命科学资讯

Epimutations driven by RNAi or heterochromatin evoke transient antimicrobial drug resistance in pathogenic Mucor fungi

Grik2b and Grik2c kainate receptors regulate oviposition in Bactrocera dorsalis

The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination

DNA damage induced by HIV-1 Vpr triggers epigenetic remodeling and transcriptional programs to enhance virus transcription and latency reactivation

Recurrent mutations in the stress regulator Cap1 reveal a trade-off between azole resistance and oxidative stress response in Candida albicans

A gut-activated NHR-86–CYP pathway mediates the neuroprotective effects of Enterococcus faecium probiotics in a nematode model of amyotrophic lateral sclerosis

Five energy metabolism pathways show distinct regional distributions and lifespan trajectories in the human brain

Correction: Intragenomic conflicts with plasmids and chromosomal mobile genetic elements drive the evolution of natural transformation within species

Microstructural profiles of the human superficial white matter and their associations to cortical geometry and connectivity

Correction: Oxygen supersaturation has negligible effects on warming tolerance across diverse aquatic ectotherms

A deep learning-based computational pipeline predicts developmental outcome in retinal organoids

The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model

The many facets of immunometabolism

Dose-dependent activation of the Hippo pathway by Type I and Type III interferons suppresses tissue repair by human bronchial epithelial cells

Dynamic auxin maxima regulate male-to-hermaphrodite conversion and de novo meristem formation in the fern Ceratopteris gametophytes

Overexpression of the pioneer transcription factor Nr5a2 promotes the development of mouse somatic cell nuclear transfer embryos

The conserved outer mitochondrial membrane protein Mtch regulates mitophagy during Drosophila intestinal development

Optineurin binding to the novel interacting partner Junction plakoglobin prevents muscle atrophy in mice

Experimental evidence that penis size, height, and body shape influence assessment of male sexual attractiveness and fighting ability in humans

Immunometabolism in obesity: Understanding the beneficial and detrimental roles of inflammation