生命科学资讯
生物技术与制药领域的最新动态
人类大脑中五种能量代谢途径呈现区域分布差异与生命周期轨迹变化
Five energy metabolism pathways show distinct regional distributions and lifespan trajectories in the human brain
更正:质粒与染色体移动遗传元件引发的基因组内冲突推动物种内自然转化的进化
Correction: Intragenomic conflicts with plasmids and chromosomal mobile genetic elements drive the evolution of natural transformation within species
人类浅层白质的微观结构特征及其与皮质几何和连接性的关联
Microstructural profiles of the human superficial white matter and their associations to cortical geometry and connectivity
修正:氧过饱和对多种水生外温动物增温耐受性影响微乎其微
Correction: Oxygen supersaturation has negligible effects on warming tolerance across diverse aquatic ectotherms
基于深度学习的计算流程预测视网膜类器官发育结果
A deep learning-based computational pipeline predicts developmental outcome in retinal organoids
脂质代谢酶HSD17B12促进PD-L1溶酶体降解,增强小鼠模型抗肿瘤免疫反应。
The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model
免疫代谢的多面性
The many facets of immunometabolism
I型和III型干扰素通过剂量依赖性激活Hippo通路抑制人支气管上皮细胞组织修复
Dose-dependent activation of the Hippo pathway by Type I and Type III interferons suppresses tissue repair by human bronchial epithelial cells
动态生长素最大值调控蕨类植物<水蕨>配子体中雄性向雌雄同体转化及新生分生组织的形成。
Dynamic auxin maxima regulate male-to-hermaphrodite conversion and de novo meristem formation in the fern Ceratopteris gametophytes
先驱转录因子Nr5a2的过表达促进小鼠体细胞核移植胚胎的发育
Overexpression of the pioneer transcription factor Nr5a2 promotes the development of mouse somatic cell nuclear transfer embryos
保守外线粒体膜蛋白Mtch在果蝇肠道发育过程中调控线粒体自噬
The conserved outer mitochondrial membrane protein Mtch regulates mitophagy during Drosophila intestinal development
Optineurin与新型相互作用伙伴Junction plakoglobin结合可预防小鼠肌肉萎缩
Optineurin binding to the novel interacting partner Junction plakoglobin prevents muscle atrophy in mice
实验证据表明,阴茎大小、身高及体型影响人类对男性性吸引力和战斗能力的评估。
Experimental evidence that penis size, height, and body shape influence assessment of male sexual attractiveness and fighting ability in humans
肥胖中的免疫代谢:理解炎症的有益与有害作用
Immunometabolism in obesity: Understanding the beneficial and detrimental roles of inflammation
泛基因组图谱分析揭示菠菜霜霉病抗性突破的进化历程
Pangenome graph analysis reveals evolution of resistance breaking in spinach downy mildew
钙信号调节果蝇中凋亡诱导的增殖
Calcium signaling regulates apoptosis-induced proliferation in Drosophila
更正:细菌基因5′端具有异常突变率,可能误导选择测试
Correction: Bacterial gene 5′ ends have unusual mutation rates that can mislead tests of selection
人类大脑中视觉、语义与记忆特征时空表征的刻画
Characterization of the spatiotemporal representations of visual, semantic, and memorability features in the human brain
通过药物和生活方式干预靶向癌症免疫代谢
Targeting immunometabolism in cancer through pharmacological and lifestyle interventions