by Qian Dong, Edel Alvarez-Ochoa, Phuong-Khanh Nguyen, Paul Orih, Natasha Fahey-Lozano, Hina Kosakamoto, Fumiaki Obata, Cyrille Alexandre, Louise Y. Cheng
Tumors adapt their metabolism to sustain increased proliferation, rendering them particularly vulnerable to fluctuations in nutrient availability. However, the role of the tumor microenvironment in modulating sensitivity to nutrient restriction (NR) remains poorly understood. Using a Drosophila brain dedifferentiation neural stem cell (NSC) t