PLoS Biology 2025年11月25日

利用合成群落进行基准测试,为Hi-C邻近连接法推断病毒-宿主关系提供基准线

by Rokaiya Nurani Shatadru, Natalie E. Solonenko, Christine L. Sun, Matthew B. Sullivan Microbiomes influence diverse ecosystems, and viruses increasingly appear to impose key constraints. While viromics has expanded genomic catalogs, host identification for these viruses remains challenging due to the limitations in scaling cultivation-based approaches and the uncertain reliability and relative low resolution of in silico predictions – particularly for understudied viral taxa. Towards this, Hi