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Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons
Publication date: 30 October 2025Source: Cell, Volume 188, Issue 22Author(s): Shuai Jin, Zixu Zhu, Yunjia Li, Shouyue Zhang, Yijing Liu, Danyuan Li, Yuanqing Li, Yingfe...
RNA Pol II inhibition activates cell death independently from the loss of transcription
Publication date: 30 October 2025Source: Cell, Volume 188, Issue 22Author(s): Nicholas W. Harper, Gavin A. Birdsall, Megan E. Honeywell, Kelly M. Ward, Athma A. Pai, Mi...
Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy
Publication date: 30 October 2025Source: Cell, Volume 188, Issue 22Author(s): Zeguang Wu, Jinhong Shi, Qiezhong Lamao, Yuanyuan Qiu, Jinxin Yang, Yang Liu, Feifei Liang...
Tumors hijack macrophages for iron supply to promote bone metastasis and anemia
Publication date: 30 October 2025Source: Cell, Volume 188, Issue 22Author(s): Yujiao Han, Hirak Sarkar, Zhan Xu, Sereno Lopez-Darwin, Yong Wei, Xiang Hang, Fengshuo Liu...
A unified cell atlas of vascular plants reveals cell-type foundational genes and accelerates gene discovery
Publication date: 30 October 2025Source: Cell, Volume 188, Issue 22Author(s): Hao-Chen Xue, Zhou-Geng Xu, Yu-Jie Liu, Long Wang, Xin Ming, Ze-Yu Wu, Heng Lian, Yu-Wei H...
Charting the landscape of cytoskeletal diversity in microbial eukaryotes
Publication date: Available online 31 October 2025Source: CellAuthor(s): Felix Mikus, Armando Rubio Ramos, Hiral Shah, Jonas Hellgoth, Marine Olivetta, Susanne Borgers,...
Coalescing single-cell genomes and transcriptomes to decode breast cancer progression
Publication date: 30 October 2025Source: Cell, Volume 188, Issue 22Author(s): Kaile Wang, Rui Ye, Shanshan Bai, Zhenna Xiao, Lei Yang, Jianzhuo Li, Chenling Tang, Emi S...
Zebrafish use spectral information to suppress the visual background
Publication date: Available online 3 November 2025Source: CellAuthor(s): Chiara Fornetto, Thomas Euler, Tom Baden
Generation of antigen-specific paired-chain antibodies using large language models
Publication date: Available online 4 November 2025Source: CellAuthor(s): Perry T. Wasdin, Nicole V. Johnson, Alexis K. Janke, Sofia Held, Toma M. Marinov, Gwen Jordaan,...
Gut-to-brain signaling restricts dietary protein intake during recovery from catabolic states
Publication date: Available online 4 November 2025Source: CellAuthor(s): Nikolai P. Jaschke, Joseph R. Luchsinger, Zuojia Chen, Vera C. Wulfmeyer, Xavier de la Rosa, Ol...
Disparate leukemia mutations converge on nuclear phase-separated condensates
Publication date: Available online 4 November 2025Source: CellAuthor(s): Gandhar K. Datar, Elmira Khabusheva, Archish Anand, Joshua Beale, Marwa Sadek, Chun-Wei Chen, E...
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Publication date: Available online 4 November 2025Source: CellAuthor(s): Hui Zhang, Tao Liu, Zhen Zhang, Samuel H. Payne, Bai Zhang, Jason E. McDermott, Jian-Ying Zhou,...
Mapping chromatin structure at base-pair resolution unveils a unified model of <em>cis</em>-regulatory element interactions
Publication date: Available online 5 November 2025Source: CellAuthor(s): Hangpeng Li, James L.T. Dalgleish, George Lister, Maria Julia Maristany, Jan Huertas, Ana M. Do...
StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models
Publication date: Available online 7 November 2025Source: CellAuthor(s): Massimo Saini, Francesc Castro-Giner, Adriana Hotz, Magdalena K. Sznurkowska, Manuel Nüesch, Fr...
Genome sequences of extant and extinct gibbons reveal their phylogeny, demographic history, and conservation status
Publication date: Available online 7 November 2025Source: CellAuthor(s): Sheng Wang, Zehui Chen, Ayun Luo, Xinran You, Andrew C. Kitchener, Xiaolong Tu, Mukesh Thakur,...
Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration
Publication date: Available online 5 November 2025Source: CellAuthor(s): Li Ping Tang, Li Ming Zhai, Jiming Li, Yue Gao, Qiu Li Ma, Rui Li, Qing Fei Liu, Wen Jie Zhang,...
Phase separation to buffer growth-mediated dilution in synthetic circuits
Publication date: Available online 7 November 2025Source: CellAuthor(s): Rong Zhang, Wangfei Yang, Rixin Zhang, Amanda Godar, Sadikshya Rijal, Abdelrahaman Youssef, Dav...
Pathway-selective 5-HT<sub>1A</sub>R agonist as a rapid antidepressant strategy
Publication date: Available online 12 November 2025Source: CellAuthor(s): Chunyu Wang, Nan Zhang, Yujie Shao, Tao Li, Mengna Zhang, Meng Gao, Yaqi Liang, Yumeng Wang, T...
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