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Budget release: Canada courts US researchers and signals wider commitment to science
Nature, Published online: 19 November 2025; doi:10.1038/d41586-025-03699-wArtificial intelligence and international scientists are some of the big winners in the countr...
Daily briefing: Kissing might have evolved 21.5 million years ago
Nature, Published online: 19 November 2025; doi:10.1038/d41586-025-03835-6Most large apes kiss, and Neanderthals probably did too. Plus, what a surge of measles in Nort...
Science on shaky ground: Canadian research shifts in the wake of US cuts
Nature, Published online: 19 November 2025; doi:10.1038/d41586-025-03724-yScientists hunt for the silver lining amid the changing funding landscape.
Shared and language-specific phonological processing in the human temporal lobe
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09748-8The human superior temporal gyrus processes acoustic–phonetic properties of speech regardless...
Rare microbial relict sheds light on an ancient eukaryotic supergroup
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09750-0The discovery of an unusual protist named Solarion arienae, which has a mitochondrial genome w...
Genetic elements promote retention of extrachromosomal DNA in cancer cells
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09764-8A combination of genome-wide functional screening, imaging and chromatin profiling identifies...
Triplets electrically turn on insulating lanthanide-doped nanoparticles
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09601-yTo turn on and obtain emission from lanthanide-doped insulating nanoparticles, an electrical e...
A skin-permeable polymer for non-invasive transdermal insulin delivery
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09729-xThe fast skin-permeable polyzwitterion poly[2-(N-oxide-N,N-dimethylamino)ethyl methacrylate] m...
Electro-generated excitons for tunable lanthanide electroluminescence
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09717-1The electroluminescence emitted from lanthanide fluoride nanocrystals functionalized with liga...
Rewiring an olfactory circuit by altering cell-surface combinatorial code
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09769-3In Drosophila, changing the expression of a small set of cell-surface proteins in just one typ...
Hepatic zonation determines tumorigenic potential of mutant β-catenin
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09733-1Zonal positioning in the liver determines whether the CTNNB1 oncogene can induce liver cancer.
Tumour-reactive heterotypic CD8 T cell clusters from clinical samples
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09754-wTumour-reactive CD8+ T cells are enriched in functional clusters with tumour cells and/or anti...
Integrator dynamics in the cortico-basal ganglia loop for flexible motor timing
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09778-2How the mouse frontal cortex and striatum interact to implement integrator dynamics controllin...
Structural basis of regulated N-glycosylation at the secretory translocon
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09756-8The structural mechanism of a natively isolated GRP94 folding intermediate tethered to a CCDC1...
Repulsions instruct synaptic partner matching in an olfactory circuit
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09768-4Transcriptomic screening identifies pairs of cell-surface proteins that mediate repulsive inte...
Insulin cream offers needle-free option for diabetes
Nature, Published online: 19 November 2025; doi:10.1038/d41586-025-03803-0Skin-permeable polymer shows promise at insulin delivery in animal experiments — plus, how the...
Prime editing-installed suppressor tRNAs for disease-agnostic genome editing
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09732-2A new strategy that uses prime editing to convert an endogenous tRNA into a suppressor tRNA sh...
Author Correction: A metallic <i>p</i>-wave magnet with commensurate spin helix
Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09861-8Author Correction: A metallic p-wave magnet with commensurate spin helix
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