Human monoclonal antibodies targeting A35 protect from death caused by mpox
#Meng Yuan#Bailey Bozarth#Hallie Cohn#Maxinne Ignacio#Patricia Earl
Life Science News
Latest updates from the biotech and pharma world
IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity
#Sara Viragova#Satoshi Koga#Meizi Liu#Publication date#memory type
Transient gene melting governs the timing of oligodendrocyte maturation
#Anushka Nikhil#Publication date#maturation Publication#Transient gene#gene melting
Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection
#Annalisa Meola#Riccardo Vernuccio#Leandro Battini#Guillermo Albericio#Pilar Delgado
Structurally conserved human anti-A35 antibodies protect mice and macaques from mpox virus infection
#Congcong Liu#Jingjing Zhang#Haonan Yang#Bing Zhou#Baoying Huang
Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons
#Shuai Jin#Zixu Zhu#Yingfeng Luo#Zhiheng Cheng#Guanglei Yang
RNA Pol II inhibition activates cell death independently from the loss of transcription
#RNA Pol#Publication date#transcription Publication#activates cell#cell death
Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy
#Jinhong Shi#Qiezhong Lamao#Yuanyuan Qiu#Feifei Liang#Wei Tang
Tumors hijack macrophages for iron supply to promote bone metastasis and anemia
#Yujiao Han#Hirak Sarkar#Fengshuo Liu#Kimberley Tran#Yong Wei
A unified cell atlas of vascular plants reveals cell-type foundational genes and accelerates gene discovery
#Xin Ming#Heng Lian#Jian Zhao#Jianghua Chen#Yanfei Mao
Charting the landscape of cytoskeletal diversity in microbial eukaryotes
#Felix Mikus#Hiral Shah#Jonas Hellgoth#Marine Olivetta#Susanne Borgers
Coalescing single-cell genomes and transcriptomes to decode breast cancer progression
#Kaile Wang#Shanshan Bai#Zhenna Xiao#Lei Yang#Chenling Tang
Zebrafish use spectral information to suppress the visual background
#Chiara Fornetto#Thomas Euler#Tom Baden#Publication date#November
Generation of antigen-specific paired-chain antibodies using large language models
#Sofia Held#Gwen Jordaan#Léna Vandenabeele#Fani Pantouli#Jeongryeol Kim
Gut-to-brain signaling restricts dietary protein intake during recovery from catabolic states
#Zuojia Chen#Oliver Hahn#Cuiling Zhang#Ruslan Medzhitov#Andrew Wang
Disparate leukemia mutations converge on nuclear phase-separated condensates
#Elmira Khabusheva#Archish Anand#Joshua Beale#Marwa Sadek#Evdokiia Potolitsyna
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
#Tao Liu#Hui Zhang#Zhen Zhang#Bai Zhang#Proteogenomic Characterization
Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
#Publication date#interactions Publication#Mapping chromatin#regulatory element#November
StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models
#Massimo Saini#Adriana Hotz#Manuel Nüesch#Selina Budinjas#Gilles Bilfeld
Genome sequences of extant and extinct gibbons reveal their phylogeny, demographic history, and conservation status
#Sheng Wang#Zehui Chen#Ayun Luo#Mukesh Thakur#Govindhaswamy Umapathy