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The efficacy of longevity interventions in <i>Caenorhabditis elegans</i> is determined by the early life activity of RNA splicing factors
by Sneha Dutta, Maria Camila Perez Matos, Caroline Heintz, Ayse Sena Mutlu, Mary Piper, Meeta Mistry, Arpit Sharma, Christopher S. Morrow, Hannah Smith, Porsha Howell,...
Efficient and reliable spike sorting from neural recordings with UMAP-based unsupervised nonlinear dimensionality reduction
by Daniel Suárez-Barrera, Lucas Bayones, Norberto Encinas-Rodríguez, Sergio Parra, Viktor Monroy, Sebastián Pujalte, Bernardo Andrade-Ortega, Héctor Díaz, Manuel Alvare...
Benchmarking with synthetic communities provides a baseline for virus-host inferences from Hi-C proximity linking
by Rokaiya Nurani Shatadru, Natalie E. Solonenko, Christine L. Sun, Matthew B. Sullivan Microbiomes influence diverse ecosystems, and viruses increasingly appear to imp...
Cardiometabolic health and physical robustness map onto distinct patterns of brain structure and neurotransmitter systems
by Eliana Nicolaisen-Sobesky, Somayeh Maleki Balajoo, Mostafa Mahdipour, Agoston Mihalik, Mahnaz Olfati, Felix Hoffstaedter, Janaina Mourao-Miranda, Masoud Tahmasian, S...
Nanobody-drug conjugates for targeting specific GPCR pairs
by Xianglin Huang, Bryan L. Roth Bitopic ligands that engage two distinct binding sites offer exciting opportunities for finely tuned control of G protein-coupled recep...
Collaborative rule learning promotes interbrain information alignment
Collaborative rule learning promotes interbrain information alignment
Episodic memory involves transient and sparse connectivity aligned to both internal and external events
Episodic memory involves transient and sparse connectivity aligned to both internal and external events
The novel GlcNAc 6-phosphate dehydratase NagS governs a metabolic checkpoint that controls nutrient signaling in <i>Streptomyces</i>
The novel GlcNAc 6-phosphate dehydratase NagS governs a metabolic checkpoint that controls nutrient signaling in Streptomyces
Context-dependent activation of V1 parvalbumin interneurons enhances visual discrimination
Context-dependent activation of V1 parvalbumin interneurons enhances visual discrimination
A novel targeting domain directs essential components of the cytosolic iron–sulfur cluster assembly pathway to the mitochondrion of <i>Toxoplasma</i> parasites
A novel targeting domain directs essential components of the cytosolic iron–sulfur cluster assembly pathway to the mitochondrion of Toxoplasma parasites
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