Endpoints News December 29, 2025

Federal judge blocks 340B drug pricing pilot ahead of Jan. 1 effective date

Fed­er­al judge blocks 340B drug pric­ing pi­lot ahead of Jan. 1 ef­fec­tive date A Maine fed­er­al judge has blocked the gov­ern­ment from im­ple­ment­ing “this it­er­a­tion” of its 340B re­bate pi­lot pro­gram “pend­ing fur­ther or­der.” Get free access to a limited number of articles, plus choose newsletters to get straight to your inbox. CMS un­veils Medicare cov­er­age mod­el for weight loss drugs Bio­haven’s ion chan­nel drug fails again, this time in ma­jor de­pres­sive dis­or­der Agios fi­nal­ly gets its tha­lassemia ap­proval Gene edit­ing's search for a 'holy grail' has led to an ex­plo­sion of tools, but few cures Ul­tragenyx, Mereo crash on late-stage bone dis­ease fail­ure Nido Bio to wind down af­ter un­der­whelm­ing Phase 2 da­ta Gen­mab ends de­vel­op­ment of Phase 3 lung can­cer as­set that BioN­Tech ditched ear­li­er ASK Pharm makes Chi­na rights deal; Uni­cy­cive re­sub­mits kid­ney drug af­ter CRL The End­points win­ners and losers list: Who was up and who was down in 2025 Bioscience & Technology Business Center